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Dynamic clonal progression in xenografts of acute lymphoblastic leukemia with intrachromosomal amplification of chromosome 21

Intrachromosomal amplification of chromosome 21 is a heterogeneous chromosomal rearrangement occurring in 2% of cases of childhood precursor B-cell acute lymphoblastic leukemia. These abnormalities are too complex to engineer faithfully in animal models and are unrepresented in leukemia cell lines....

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Detalhes bibliográficos
Publicado no:Haematologica
Main Authors: Sinclair, Paul. B., Blair, Helen H., Ryan, Sarra L., Buechler, Lars, Cheng, Joanna, Clayton, Jake, Hanna, Rebecca, Hollern, Shaun, Hawking, Zoe, Bashton, Matthew, Schwab, Claire J., Jones, Lisa, Russell, Lisa J., Marr, Helen, Carey, Peter, Halsey, Christina, Heidenreich, Olaf, Moorman, Anthony V., Harrison, Christine J.
Formato: Artigo
Idioma:Inglês
Publicado em: Ferrata Storti Foundation 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5865429/
https://ncbi.nlm.nih.gov/pubmed/29449437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2017.172304
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