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Concordance of copy number abnormality detection using SNP arrays and Multiplex Ligation-dependent Probe Amplification (MLPA) in acute lymphoblastic leukaemia

In acute lymphoblastic leukaemia, MLPA has been used in research studies to identify clinically relevant copy number abnormality (CNA) profiles. However, in diagnostic settings other techniques are often employed. We assess whether equivalent CNA profiles are called using SNP arrays, ensuring platfo...

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Publicat a:Sci Rep
Autors principals: Bashton, Matthew, Hollis, Robin, Ryan, Sarra, Schwab, Claire J., Moppett, John, Harrison, Christine J., Moorman, Anthony V., Enshaei, Amir
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2020
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6949215/
https://ncbi.nlm.nih.gov/pubmed/31913349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-56972-0
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