Quantitative copy number analysis by Multiplex Ligation-dependent Probe Amplification (MLPA) of BRCA1-associated breast cancer regions identifies BRCAness

INTRODUCTION: Our group has previously employed array Comparative Genomic Hybridization (aCGH) to assess the genomic patterns of BRCA1-mutated breast cancers. We have shown that the so-called BRCA1-like(aCGH )profile is also present in about half of all triple-negative sporadic breast cancers and is...

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Detalhes bibliográficos
Main Authors: Lips, Esther H, Laddach, Nadja, Savola, Suvi P, Vollebergh, Marieke A, Oonk, Anne MM, Imholz, Alex LT, Wessels, Lodewyk FA, Wesseling, Jelle, Nederlof, Petra M, Rodenhuis, Sjoerd
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3262220/
https://ncbi.nlm.nih.gov/pubmed/22032731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr3049
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