Triple-negative breast cancer: BRCAness and concordance of clinical features with BRCA1-mutation carriers

BACKGROUND: BRCAness is defined as shared tumour characteristics between sporadic and BRCA-mutated cancers. However, how to exactly measure BRCAness and its frequency in breast cancer is not known. Assays to establish BRCAness would be extremely valuable for the clinical management of these tumours....

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Dettagli Bibliografici
Autori principali: Lips, E H, Mulder, L, Oonk, A, van der Kolk, L E, Hogervorst, F B L, Imholz, A L T, Wesseling, J, Rodenhuis, S, Nederlof, P M
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2013
Soggetti:
Genetics and Genomics
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3670471/
https://ncbi.nlm.nih.gov/pubmed/23558900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2013.144
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