Triple-negative breast cancer: BRCAness and concordance of clinical features with BRCA1-mutation carriers

BACKGROUND: BRCAness is defined as shared tumour characteristics between sporadic and BRCA-mutated cancers. However, how to exactly measure BRCAness and its frequency in breast cancer is not known. Assays to establish BRCAness would be extremely valuable for the clinical management of these tumours....

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Detalhes bibliográficos
Main Authors: Lips, E H, Mulder, L, Oonk, A, van der Kolk, L E, Hogervorst, F B L, Imholz, A L T, Wesseling, J, Rodenhuis, S, Nederlof, P M
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
Assuntos:
Genetics and Genomics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3670471/
https://ncbi.nlm.nih.gov/pubmed/23558900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2013.144
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