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Probe-specific mixed-model approach to detect copy number differences using multiplex ligation-dependent probe amplification (MLPA)
<p>Abstract</p> <p>Background</p> <p>MLPA method is a potentially useful semi-quantitative method to detect copy number alterations in targeted regions. In this paper, we propose a method for the normalization procedure based on a non-linear mixed-model, as well as a ne...
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| Autori principali: | , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
BMC
2008-06-01
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| Serie: | BMC Bioinformatics |
| Accesso online: | http://www.biomedcentral.com/1471-2105/9/261 |
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