UBASH3B/Sts-1-CBL axis regulates myeloid proliferation in human preleukemia induced by AML1-ETO

The t(8;21) rearrangement, which creates the AML1-ETO fusion protein, represents the most common chromosomal translocation in acute myeloid leukemia (AML). Clinical data suggest that CBL mutations are a frequent event in t(8;21) AML, but the role of CBL in AML1-ETO-induced leukemia has not been inve...

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Udgivet i:Leukemia
Main Authors: Goyama, Susumu, Schibler, Janet, Gasilina, Anjelika, Shrestha, Mahesh, Lin, Shan, Link, Kevin A., Chen, Jianjun, Whitman, Susan P., Bloomfield, Clara D., Nicolet, Deedra, Assi, Salam, Ptasinska, Anetta, Heidenreich, Olaf, Bonifer, Constanze, Kitamura, Toshio, Nassar, Nicolas N., Mulloy, James C.
Format: Artigo
Sprog:Inglês
Udgivet: 2015
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4775400/
https://ncbi.nlm.nih.gov/pubmed/26449661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/leu.2015.275
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