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A Drosophila model identifies calpains as modulators of the human leukemogenic fusion protein AML1-ETO
The t(8:21)(q22;q22) translocation is 1 of the most common chromosomal abnormalities linked to acute myeloid leukemia (AML). AML1-ETO, the product of this translocation, fuses the N-terminal portion of the RUNX transcription factor AML1 (also known as RUNX1), including its DNA-binding domain, to the...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2715513/ https://ncbi.nlm.nih.gov/pubmed/19581587 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0902449106 |
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