A Drosophila model identifies calpains as modulators of the human leukemogenic fusion protein AML1-ETO

The t(8:21)(q22;q22) translocation is 1 of the most common chromosomal abnormalities linked to acute myeloid leukemia (AML). AML1-ETO, the product of this translocation, fuses the N-terminal portion of the RUNX transcription factor AML1 (also known as RUNX1), including its DNA-binding domain, to the...

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Detaylı Bibliyografya
Asıl Yazarlar: Osman, Dani, Gobert, Vanessa, Ponthan, Frida, Heidenreich, Olaf, Haenlin, Marc, Waltzer, Lucas
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2009
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2715513/
https://ncbi.nlm.nih.gov/pubmed/19581587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0902449106
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