The Leukemogenicity of AML1-ETO Is Dependent on Site-Specific Lysine Acetylation

The chromosomal translocations found in acute myelogenous leukemia (AML) generate oncogenic fusion transcription factors with aberrant transcriptional regulatory properties. Although therapeutic targeting of most leukemia fusion proteins remains elusive, the posttranslational modifications that cont...

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Detaylı Bibliyografya
Asıl Yazarlar: Wang, Lan, Gural, Alexander, Sun, Xiao-Jian, Zhao, Xinyang, Perna, Fabiana, Huang, Gang, Hatlen, Megan A., Vu, Ly, Liu, Fan, Xu, Haiming, Asai, Takashi, Xu, Hao, Deblasio, Tony, Menendez, Silvia, Voza, Francesca, Jiang, Yanwen, Cole, Philip A., Zhang, Jinsong, Melnick, Ari, Roeder, Robert G., Nimer, Stephen D.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2011
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3251012/
https://ncbi.nlm.nih.gov/pubmed/21764752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1201662
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