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The Leukemogenicity of AML1-ETO Is Dependent on Site-Specific Lysine Acetylation
The chromosomal translocations found in acute myelogenous leukemia (AML) generate oncogenic fusion transcription factors with aberrant transcriptional regulatory properties. Although therapeutic targeting of most leukemia fusion proteins remains elusive, the posttranslational modifications that cont...
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| Hlavní autoři: | , , , , , , , , , , , , , , , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2011
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3251012/ https://ncbi.nlm.nih.gov/pubmed/21764752 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1201662 |
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