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A stable transcription factor complex nucleated by oligomeric AML1-ETO controls leukaemogenesis
Transcription factors are frequently altered in leukaemia through chromosomal translocation, mutation or aberrant expression(1). AML1-ETO, a fusion protein generated by the t(8;21) translocation in acute myeloid leukaemia (AML), is a transcription factor implicated in both gene repression and activa...
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| Hauptverfasser: | , , , , , , , , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3732535/ https://ncbi.nlm.nih.gov/pubmed/23812588 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature12287 |
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