A novel epigenetic AML1‐ETO/THAP10/miR‐383 mini‐circuitry contributes to t(8;21) leukaemogenesis

DNA methylation patterns are frequently deregulated in t(8;21) acute myeloid leukaemia (AML), but little is known of the mechanisms by which specific gene sets become aberrantly methylated. Here, we found that the promoter DNA methylation signature of t(8;21)(+) AML blasts differs from that of t(8;2...

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Vydáno v:EMBO Mol Med
Hlavní autoři: Li, Yonghui, Ning, Qiaoyang, Shi, Jinlong, Chen, Yang, Jiang, Mengmeng, Gao, Li, Huang, Wenrong, Jing, Yu, Huang, Sai, Liu, Anqi, Hu, Zhirui, Liu, Daihong, Wang, Lili, Nervi, Clara, Dai, Yun, Zhang, Michael Q, Yu, Li
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2017
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Research Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5577530/
https://ncbi.nlm.nih.gov/pubmed/28539478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/emmm.201607180
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