Perturbation of fetal liver hematopoietic stem and progenitor cell development by trisomy 21

The 40-fold increase in childhood megakaryocyte-erythroid and B-cell leukemia in Down syndrome implicates trisomy 21 (T21) in perturbing fetal hematopoiesis. Here, we show that compared with primary disomic controls, primary T21 fetal liver (FL) hematopoietic stem cells (HSC) and megakaryocyte-eryth...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Roy, Anindita, Cowan, Gillian, Mead, Adam J., Filippi, Sarah, Bohn, Georg, Chaidos, Aristeidis, Tunstall, Oliver, Chan, Jerry K. Y., Choolani, Mahesh, Bennett, Phillip, Kumar, Sailesh, Atkinson, Deborah, Wyatt-Ashmead, Josephine, Hu, Ming, Stumpf, Michael P. H., Goudevenou, Katerina, O'Connor, David, Chou, Stella T., Weiss, Mitchell J., Karadimitris, Anastasios, Jacobsen, Sten Eirik, Vyas, Paresh, Roberts, Irene
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2012
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3491522/
https://ncbi.nlm.nih.gov/pubmed/23045701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1211405109
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados