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The impact of trisomy 21 on foetal haematopoiesis

The high frequency of a unique neonatal preleukaemic syndrome, Transient Abnormal Myelopoiesis (TAM), and subsequent acute myeloid leukaemia in early childhood in patients with trisomy 21 (Down syndrome) points to a specific role for trisomy 21 in transforming foetal haematopoietic cells. N-terminal...

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Bibliographic Details
Published in:Blood Cells Mol Dis
Main Authors: Roberts, Irene, O'Connor, David, Roy, Anindita, Cowan, Gillian, Vyas, Paresh
Format: Artigo
Language:Inglês
Published: 2013
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4727253/
https://ncbi.nlm.nih.gov/pubmed/23932236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcmd.2013.07.008
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