A dynamic niche provides Kit ligand in a stage-specific manner to the earliest thymocyte progenitors

Thymic T-cell development is initiated from bone marrow-derived multi-potent thymus seeding progenitors (TSPs). During the early stages of thymocyte differentiation progenitors become T-cell restricted. However, the cellular environments supporting these critical initial stages of T-cell development...

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Detalhes bibliográficos
Publicado no:Nat Cell Biol
Main Authors: Buono, Mario, Facchini, Raffaella, Matsuoka, Sahoko, Thongjuea, Supat, Waithe, Dominique, Luis, Tiago C., Giustacchini, Alice, Besmer, Peter, Mead, Adam J., Jacobsen, Sten Eirik W., Nerlov, Claus
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4972409/
https://ncbi.nlm.nih.gov/pubmed/26780297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb3299
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