Cordycepin Blocks Lung Injury-Associated Inflammation and Promotes BRCA1-Deficient Breast Cancer Cell Killing by Effectively Inhibiting PARP

por Kim, Hogyoung, Naura, Amarjit S, Errami, Youssef, Ju, Jihang, Boulares, A Hamid
Publicado 2011

One-step generation of modular CAR-T with AAV-Cpf1

por Dai, Xiaoyun, Park, Jonathan J., Du, Yaying, Kim, Hyunu R., Wang, Guangchuan, Errami, Youssef, Chen, Sidi
Publicado en Nat Methods (2019)

HIGH FAT DIET INDUCES LUNG REMODELING IN APOE DEFICIENT MICE: AN ASSOCIATION WITH AN INCREASE IN CIRCULATORY AND LUNG INFLAMMATORY FACTORS

por Naura, Amarjit S., Hans, Chetan P., Zerfaoui, Mourad, Errami, Youssef, Ju, Jihang, Kim, Hogyoung, Matrougui, Khalid, Kim, Jong G., Boulares, A. Hamid
Publicado 2009

In vivo profiling of metastatic double knockouts through CRISPR-Cpf1 screens

por Chow, Ryan D., Wang, Guangchuan, Ye, Lupeng, Codina, Adan, Kim, Hyunu Ray, Shen, Li, Dong, Matthew B., Errami, Youssef, Chen, Sidi
Publicado en Nat Methods (2019)

PARP-1 deficiency blocks IL-5 expression through calpain-dependent degradation of STAT-6 in a murine asthma model

por Datta, Rahul, Naura, Amarjit S., Zerfaoui, Mourad, Errami, Youssef, Oumouna, Mustapha, Kim, Hogyoung, Ju, Jihang, Ronchi, Virginia P, Haas, Arthur L., Boulares, A. Hamid
Publicado 2011

Effects of PARP-1 deficiency on airway inflammatory cell recruitment in response to LPS or TNF: differential effects on CXCR2 ligands and Duffy antigen receptor for chemokines

por Zerfaoui, Mourad, Naura, Amarjit S., Errami, Youssef, Hans, Chetan P., Rezk, Bashir M., Park, Jiwon, Elsegeiny, Waleed, Kim, Hogyoung, Lord, Kevin, Kim, Jong G., Boulares, A. Hamid
Publicado 2009

In vivo CRISPR screening in CD8 T cells with AAV-Sleeping Beauty hybrid vectors identifies membrane targets for improving immunotherapy for glioblastoma

por Ye, Lupeng, Park, Jonathan J., Dong, Matthew B., Yang, Quanjun, Chow, Ryan D., Peng, Lei, Du, Yaying, Guo, Jianjian, Dai, Xiaoyun, Wang, Guangchuan, Errami, Youssef, Chen, Sidi
Publicado en Nat Biotechnol (2019)

Requirement for Inducible Nitric Oxide Synthase in Chronic Allergen Exposure-Induced Pulmonary Fibrosis but Not Inflammation

por Naura, Amarjit S., Zerfaoui, Mourad, Kim, Hogyoung, Abd Elmageed, Zakaria Y., Rodriguez, Paulo C., Hans, Chetan P., Ju, Jihang, Errami, Youssef, Park, Jiwon, Ochoa, Augusto C., Boulares, A. Hamid
Publicado 2010

Mbd3/NuRD controls lymphoid cell fate and inhibits tumorigenesis by repressing a B cell transcriptional program

por Loughran, Stephen J., Comoglio, Federico, Hamey, Fiona K., Giustacchini, Alice, Errami, Youssef, Earp, Eleanor, Göttgens, Berthold, Jacobsen, Sten Eirik W., Mead, Adam J., Hendrich, Brian, Green, Anthony R.
Publicado en J Exp Med (2017)

POLY(ADP-RIBOSE) POLYMERASE-1 IS A DETERMINING FACTOR IN CRM1-MEDIATED NUCLEAR EXPORT AND RETENTION OF P65 NF-κB UPON TLR4 STIMULATION

por Zerfaoui, Mourad, Errami, Youssef, Naura, Amarjit S., Suzuki, Yasuhiro, Kim, Hogyoung, Ju, Jihang, Liu, Tao, Hans, Chetan P., Kim, Jong G., Abd Elmageed, Zakaria Y., Koochekpour, Shahriar, Catling, Andrew, Boulares, A. Hamid
Publicado 2010

Phosphorylation of p50 NF-κB at a Single Serine Residue by DNA-dependent Protein Kinase Is Critical for VCAM-1 Expression upon TNF Treatment

por Ju, Jihang, Naura, Amarjit S., Errami, Youssef, Zerfaoui, Mourad, Kim, Hogyoung, Kim, Jong G., Elmageed, Zakaria Y. Abd, Abdel-Mageed, Asim B., Giardina, Charles, Beg, Amer A., Smulson, Mark E., Boulares, A. Hamid
Publicado 2010

Apoptotic DNA Fragmentation May Be a Cooperative Activity between Caspase-activated Deoxyribonuclease and the Poly(ADP-ribose) Polymerase-regulated DNAS1L3, an Endoplasmic Reticulu...

por Errami, Youssef, Naura, Amarjit S., Kim, Hogyoung, Ju, Jihang, Suzuki, Yasuhiro, El-Bahrawy, Ali H., Ghonim, Mohamed A., Hemeida, Ramadan A., Mansy, Moselhy S., Zhang, Jianhua, Xu, Ming, Smulson, Mark E., Brim, Hassan, Boulares, A. Hamid
Publicado 2013

Multiplexed activation of endogenous genes by CRISPRa elicits potent anti-tumor immunity

por Wang, Guangchuan, Chow, Ryan D., Bai, Zhigang, Zhu, Lvyun, Errami, Youssef, Dai, Xiaoyun, Dong, Matthew B., Ye, Lupeng, Zhang, Xiaoya, Renauer, Paul A., Park, Jonathan J., Shen, Li, Ye, Hanghui, Fuchs, Charles S., Chen, Sidi
Publicado en Nat Immunol (2019)

ICAD Deficiency in Human Colon Cancer and Predisposition to Colon Tumorigenesis: Linkage to Apoptosis Resistance and Genomic Instability

por Errami, Youssef, Brim, Hassan, Oumouna-Benachour, Karine, Oumouna, Mustapha, Naura, Amarjit S., Kim, Hogyoung, Ju, Jihang, Davis, Christian J., Kim, Jong G., Ashktorab, Hassan, Fallon, Kenneth, Xu, Ming, Zhang, Jianhua, Valle, Luis Del, Boulares, A. Hamid
Publicado 2013

Minocycline Blocks Asthma-associated Inflammation in Part by Interfering with the T Cell Receptor-Nuclear Factor κB-GATA-3-IL-4 Axis without a Prominent Effect on Poly(ADP-ribose)...

por Naura, Amarjit S., Kim, Hogyoung, Ju, Jihang, Rodriguez, Paulo C., Jordan, Joaquin, Catling, Andrew D., Rezk, Bashir M., Elmageed, Zakaria Y. Abd, Pyakurel, Kusma, Tarhuni, Abdelmetalab F., Abughazleh, Mohammad Q., Errami, Youssef, Zerfaoui, Mourad, Ochoa, Augusto C., Boulares, A. Hamid
Publicado 2013

Targeting PARP-1 with metronomic therapy modulates MDSC suppressive function and enhances anti-PD-1 immunotherapy in colon cancer

por Ghonim, Mohamed A, Ibba, Salome V, Tarhuni, Abdelmetalab F, Errami, Youssef, Luu, Hanh H, Dean, Matthew J, El-Bahrawy, Ali H, Wyczechowska, Dorota, Benslimane, Ilyes A, Del Valle, Luis, Al-Khami, Amir A, Ochoa, Augusto C, Boulares, A Hamid
Publicado en J Immunother Cancer (2021)

AAV-mediated direct in vivo CRISPR screen identifies functional suppressors in glioblastoma

por Chow, Ryan D., Guzman, Christopher D., Wang, Guangchuan, Schmidt, Florian, Youngblood, Mark W., Ye, Lupeng, Errami, Youssef, Dong, Matthew B., Martinez, Michael A., Zhang, Sensen, Renauer, Paul, Bilguvar, Kaya, Gunel, Murat, Sharp, Phillip A., Zhang, Feng, Platt, Randall J., Chen, Sidi
Publicado en Nat Neurosci (2017)

Convergent identification and interrogation of tumor-intrinsic factors that modulate cancer immunity in vivo

por Codina, Adan, Renauer, Paul A., Wang, Guangchuan, Chow, Ryan D., Park, Jonathan J., Ye, Hanghui, Zhang, Kerou, Dong, Matthew, Gassaway, Brandon, Ye, Lupeng, Errami, Youssef, Shen, Li, Chang, Alan, Jain, Dhanpat, Herbst, Roy S., Bosenberg, Marcus, Rinehart, Jesse, Fan, Rong, Chen, Sidi
Publicado en Cell Syst (2019)

CRISPR-GEMM pooled mutagenic screening identifies KMT2D as a major modulator of immune checkpoint blockade

por Wang, Guangchuan, Chow, Ryan D., Zhu, Lvyun, Bai, Zhigang, Ye, Lupeng, Zhang, Feifei, Renauer, Paul A., Dong, Matthew B., Dai, Xiaoyun, Zhang, Xiaoya, Du, Yaying, Cheng, Yujing, Niu, Leilei, Chu, Zhiyuan, Kim, Kristin, Liao, Cun, Clark, Paul, Errami, Youssef, Chen, Sidi
Publicado en Cancer Discov (2020)

Systematic immunotherapy target discovery using genome-scale in vivo CRISPR screens in CD8 T cells

por Dong, Matthew B., Wang, Guangchuan, Chow, Ryan D., Ye, Lupeng, Zhu, Lvyun, Dai, Xiaoyun, Park, Jonathan J., Kim, Hyunu R., Errami, Youssef, Guzman, Christopher D., Zhou, Xiaoyu, Chen, Krista, Renauer, Paul A., Du, Yaying, Shen, Johanna, Lam, Stanley, Zhou, Jerry, Lannin, Donald R., Herbst, Roy S., Chen, Sidi
Publicado en Cell (2019)