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Myeloproliferative neoplasm stem cells

Myeloproliferative neoplasms (MPNs) arise in the hematopoietic stem cell (HSC) compartment as a result of the acquisition of somatic mutations in a single HSC that provides a selective advantage to mutant HSC over normal HSC and promotes myeloid differentiation to engender a myeloproliferative pheno...

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Bibliographic Details
Published in:Blood
Main Authors: Mead, Adam J., Mullally, Ann
Format: Artigo
Language:Inglês
Published: American Society of Hematology 2017
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5413298/
https://ncbi.nlm.nih.gov/pubmed/28159736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2016-10-696005
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