Prescience of a Surgeon in 1980

Por McLachlan, Sandra M.
Publicado em 2013

Thyroid autoimmunity

Por Rapoport, Basil, McLachlan, Sandra M.
Publicado em 2001

Thyrotropin-Blocking Autoantibodies and Thyroid-Stimulating Autoantibodies: Potential Mechanisms Involved in the Pendulum Swinging from Hypothyroidism to Hyperthyroidism or Vice Ve...

Por McLachlan, Sandra M., Rapoport, Basil
Publicado em 2013

Breaking Tolerance to Thyroid Antigens: Changing Concepts in Thyroid Autoimmunity

Por McLachlan, Sandra M., Rapoport, Basil
Publicado em 2014

Graves' Hyperthyroidism Is Antibody-Mediated But Is Predominantly a Th1-Type Cytokine Disease

Por Rapoport, Basil, McLachlan, Sandra M.
Publicado no J Clin Endocrinol Metab (2014)

TSH Receptor Cleavage Into Subunits and Shedding of the A-Subunit; A Molecular and Clinical Perspective

Por Rapoport, Basil, McLachlan, Sandra M.
Publicado no Endocr Rev (2016)

Review and Hypothesis: Does Graves' Disease Develop in Non-Human Great Apes?

Por McLachlan, Sandra M., Alpi, Kristine, Rapoport, Basil
Publicado em 2011

Identification of Key Amino Acid Residues in a Thyrotropin Receptor Monoclonal Antibody Epitope Provides Insight into Its Inverse Agonist and Antagonist Properties

Por Chen, Chun-Rong, McLachlan, Sandra M., Rapoport, Basil
Publicado em 2008

A Monoclonal Antibody with Thyrotropin (TSH) Receptor Inverse Agonist and TSH Antagonist Activities Binds to the Receptor Hinge Region as Well as to the Leucine-Rich Domain

Por Chen, Chun-Rong, McLachlan, Sandra M., Rapoport, Basil
Publicado em 2009

Thyrotropin (TSH) Receptor Residue E251 in the Extracellular Leucine-Rich Repeat Domain Is Critical for Linking TSH Binding to Receptor Activation

Por Chen, Chun-Rong, McLachlan, Sandra M., Rapoport, Basil
Publicado em 2010

Thyroid Antigens, Not Central Tolerance, Control Responses to Immunization in BALB/c Versus C57BL/6 Mice

Por Misharin, Alexander V., Rapoport, Basil, McLachlan, Sandra M.
Publicado em 2009

Evidence That the Thyroid-stimulating Hormone (TSH) Receptor Transmembrane Domain Influences Kinetics of TSH Binding to the Receptor Ectodomain

Por Chen, Chun-Rong, McLachlan, Sandra M., Rapoport, Basil
Publicado em 2011

The Thyrotropin Receptor Hinge Region Is Not Simply a Scaffold for the Leucine-Rich Domain but Contributes to Ligand Binding and Signal Transduction

Por Mizutori, Yumiko, Chen, Chun-Rong, McLachlan, Sandra M., Rapoport, Basil
Publicado em 2008

Insight into Thyroid-Stimulating Autoantibody Interaction with the Thyrotropin Receptor N-Terminus Based on Mutagenesis and Re-Evaluation of Ambiguity in This Region of the Recepto...

Por Hamidi, Sepehr, Chen, Chun-Rong, McLachlan, Sandra M., Rapoport, Basil
Publicado em 2011

Thyroid Autoantibodies Are Rare in Nonhuman Great Apes and Hypothyroidism Cannot Be Attributed to Thyroid Autoimmunity

Por Aliesky, Holly, Courtney, Cynthia L., Rapoport, Basil, McLachlan, Sandra M.
Publicado em 2013

An Attempt to Induce “Graves' Disease of the Gonads” by Immunizing Mice with the Luteinizing Hormone Receptor Provides Insight into Breaking Tolerance to Self-Antigens

Por Chen, Chun-Rong, Aliesky, Holly A., Rapoport, Basil, McLachlan, Sandra M.
Publicado em 2011

Novel Information on the Epitope of an Inverse Agonist Monoclonal Antibody Provides Insight into the Structure of the TSH Receptor

Por Chen, Chun-Rong, Salazar, Larry M., McLachlan, Sandra M., Rapoport, Basil
Publicado em 2012

Role of Self-Tolerance and Chronic Stimulation in the Long-Term Persistence of Adenovirus-Induced Thyrotropin Receptor Antibodies in Wild-Type and Transgenic Mice

Por McLachlan, Sandra M., Aliesky, Holly A., Chen, Chun-Rong, Rapoport, Basil
Publicado em 2012

The Thyrotropin Receptor Hinge Region as a Surrogate Ligand: Identification of Loci Contributing to the Coupling of Thyrotropin Binding and Receptor Activation

Por Chen, Chun-Rong, Salazar, Larry M., McLachlan, Sandra M., Rapoport, Basil
Publicado em 2012

IMMUNOGLOBULIN HEAVY CHAIN VARIABLE REGION GENES CONTRIBUTE TO THE INDUCTION OF THYROID STIMULATING ANTIBODIES IN RECOMBINANT INBRED MICE

Por Rapoport, Basil, Williams, Robert W., Chen, Chun-Rong, McLachlan, Sandra M.
Publicado em 2010