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Breaking Tolerance to Thyroid Antigens: Changing Concepts in Thyroid Autoimmunity

Thyroid autoimmunity involves loss of tolerance to thyroid proteins in genetically susceptible individuals in association with environmental factors. In central tolerance, intrathymic autoantigen presentation deletes immature T cells with high affinity for autoantigen-derived peptides. Regulatory T...

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Detalhes bibliográficos
Main Authors: McLachlan, Sandra M., Rapoport, Basil
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3895862/
https://ncbi.nlm.nih.gov/pubmed/24091783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/er.2013-1055
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