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Breaking Tolerance to Thyroid Antigens: Changing Concepts in Thyroid Autoimmunity

Thyroid autoimmunity involves loss of tolerance to thyroid proteins in genetically susceptible individuals in association with environmental factors. In central tolerance, intrathymic autoantigen presentation deletes immature T cells with high affinity for autoantigen-derived peptides. Regulatory T...

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Detaylı Bibliyografya
Asıl Yazarlar: McLachlan, Sandra M., Rapoport, Basil
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Endocrine Society 2014
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3895862/
https://ncbi.nlm.nih.gov/pubmed/24091783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/er.2013-1055
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