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Breaking Tolerance to Thyroid Antigens: Changing Concepts in Thyroid Autoimmunity
Thyroid autoimmunity involves loss of tolerance to thyroid proteins in genetically susceptible individuals in association with environmental factors. In central tolerance, intrathymic autoantigen presentation deletes immature T cells with high affinity for autoantigen-derived peptides. Regulatory T...
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| Main Authors: | , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Endocrine Society
2014
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3895862/ https://ncbi.nlm.nih.gov/pubmed/24091783 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/er.2013-1055 |
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