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Breaking Tolerance to Thyroid Antigens: Changing Concepts in Thyroid Autoimmunity

Thyroid autoimmunity involves loss of tolerance to thyroid proteins in genetically susceptible individuals in association with environmental factors. In central tolerance, intrathymic autoantigen presentation deletes immature T cells with high affinity for autoantigen-derived peptides. Regulatory T...

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Bibliografische gegevens
Hoofdauteurs: McLachlan, Sandra M., Rapoport, Basil
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Endocrine Society 2014
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3895862/
https://ncbi.nlm.nih.gov/pubmed/24091783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/er.2013-1055
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