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Thyroid Autoantibodies Display both “Original Antigenic Sin” and Epitope Spreading
Evidence for original antigenic sin in spontaneous thyroid autoimmunity is revealed by autoantibody interactions with immunodominant regions on thyroid autoantigens, thyroglobulin (Tg), thyroid peroxidase (TPO), and the thyrotropin receptor (TSHR) A-subunit. In contrast, antibodies induced by immuni...
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| Publicado en: | Front Immunol |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Frontiers Media S.A.
2017
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5742354/ https://ncbi.nlm.nih.gov/pubmed/29326719 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.01845 |
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