The Thyrotropin Receptor Hinge Region Is Not Simply a Scaffold for the Leucine-Rich Domain but Contributes to Ligand Binding and Signal Transduction

Lignende værker

• The Thyrotropin Receptor Hinge Region as a Surrogate Ligand: Identification of Loci Contributing to the Coupling of Thyrotropin Binding and Receptor Activation
  af: Chen, Chun-Rong, et al.
  Udgivet: (2012)
• A Monoclonal Antibody with Thyrotropin (TSH) Receptor Inverse Agonist and TSH Antagonist Activities Binds to the Receptor Hinge Region as Well as to the Leucine-Rich Domain
  af: Chen, Chun-Rong, et al.
  Udgivet: (2009)
• Relationship between Thyrotropin Receptor Hinge Region Proteolytic Posttranslational Modification and Receptor Physiological Function
  af: Hamidi, Sepehr, et al.
  Udgivet: (2011)
• Thyrotropin (TSH) Receptor Residue E251 in the Extracellular Leucine-Rich Repeat Domain Is Critical for Linking TSH Binding to Receptor Activation
  af: Chen, Chun-Rong, et al.
  Udgivet: (2010)
• Evidence that Shed Thyrotropin Receptor A Subunits Drive Affinity Maturation of Autoantibodies Causing Graves’ Disease
  af: Mizutori, Yumiko, et al.
  Udgivet: (2009)