Loading...

The Thyrotropin Receptor Hinge Region as a Surrogate Ligand: Identification of Loci Contributing to the Coupling of Thyrotropin Binding and Receptor Activation

The TSH receptor (TSHR) hinge region, the least well understood component, bridges the leucine-rich repeat and transmembrane domains. We report data on clusters of hinge charged residues the mutation of which to Ala is compatible with cell surface expression and normal, or near normal, TSH binding a...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Chen, Chun-Rong, Salazar, Larry M., McLachlan, Sandra M., Rapoport, Basil
Format: Artigo
Sprog:Inglês
Udgivet: Endocrine Society 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3512008/
https://ncbi.nlm.nih.gov/pubmed/23002040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2012-1376
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!