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Relationship between Thyrotropin Receptor Hinge Region Proteolytic Posttranslational Modification and Receptor Physiological Function

The glycoprotein hormone receptor hinge region is the least conserved component and the most variable in size; the TSH receptor (TSHR) being the longest (152 amino acids; residues 261–412). The TSHR is also unique among the glycoprotein hormone receptor in undergoing in vivo intramolecular cleavage...

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Detalhes bibliográficos
Main Authors: Hamidi, Sepehr, Chen, Chun-Rong, Mizutori-Sasai, Yumiko, McLachlan, Sandra M., Rapoport, Basil
Formato: Artigo
Idioma:Inglês
Publicado em: The Endocrine Society 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3089032/
https://ncbi.nlm.nih.gov/pubmed/21106880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2010-0401
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