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TSH Receptor Cleavage Into Subunits and Shedding of the A-Subunit; A Molecular and Clinical Perspective

The TSH receptor (TSHR) on the surface of thyrocytes is unique among the glycoprotein hormone receptors in comprising two subunits: an extracellular A-subunit, and a largely transmembrane and cytosolic B-subunit. Unlike its ligand TSH, whose subunits are encoded by two genes, the TSHR is expressed a...

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書目詳細資料
發表在:Endocr Rev
Main Authors: Rapoport, Basil, McLachlan, Sandra M.
格式: Artigo
語言:Inglês
出版: Endocrine Society 2016
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4823380/
https://ncbi.nlm.nih.gov/pubmed/26799472
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/er.2015-1098
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