Lataa...
Evidence that TSH Receptor A-Subunit Multimers, Not Monomers, Drive Antibody Affinity Maturation in Graves' Disease
CONTEXT: The TSH receptor (TSHR) A-subunit shed from the cell surface contributes to the induction and/or affinity maturation of pathogenic TSHR autoantibodies in Graves' disease. OBJECTIVE: This study aimed to determine whether the quaternary structure (multimerization) of shed A-subunits infl...
Tallennettuna:
| Julkaisussa: | J Clin Endocrinol Metab |
|---|---|
| Päätekijät: | , , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
Endocrine Society
2015
|
| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4454809/ https://ncbi.nlm.nih.gov/pubmed/25856215 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2015-1528 |
| Tagit: |
Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!
|