Malignant Glioma: Lessons from Genomics, Mouse Models, and Stem Cells

por Chen, Jian, McKay, Renée M., Parada, Luis F.
Publicado em 2012

REDD1/DDIT4-independent mTORC1 Inhibition and Apoptosis by Glucocorticoids in Thymocytes

por Wolff, Nicholas C., McKay, Renée M., Brugarolas, James
Publicado no Mol Cancer Res (2014)

Neurofibromin Modulates Adult Hippocampal Neurogenesis and Behavioral Effects of Antidepressants

por Li, Yun, Li, Yanjiao, McKay, Renée M., Riethmacher, Dieter, Parada, Luis F.
Publicado em 2012

C. elegans: A Model for Exploring the Genetics of Fat Storage

por McKay, Renée M., McKay, James P., Avery, Leon, Graff, Jonathan M.
Publicado no Dev Cell (2003)

Glioblastoma multiforme: a perspective on recent findings in human cancer and mouse models

por Lim, Sang Kyun, Llaguno, Sheila R. Alcantara, McKay, Renée M., Parada, Luis F.
Publicado em 2011

Tripeptidyl peptidase II promotes fat formation in a conserved fashion

por McKay, Renée M, McKay, James P, Suh, Jae Myoung, Avery, Leon, Graff, Jonathan M
Publicado em 2007

Tsc1 mutant neural stem/progenitor cells exhibit migration deficits and give rise to subependymal lesions in the lateral ventricle

por Zhou, Jing, Shrikhande, Gayatri, Xu, Jing, McKay, Renée M., Burns, Dennis K., Johnson, Jane E., Parada, Luis F.
Publicado em 2011

Conditional ablation of brain-derived neurotrophic factor-TrkB signaling impairs striatal neuron development

por Li, Yun, Yui, Daishi, Luikart, Bryan W., McKay, Renée M., Li, Yanjiao, Rubenstein, John L., Parada, Luis F.
Publicado em 2012

Pten Deletion in Adult Hippocampal Neural Stem/Progenitor Cells Causes Cellular Abnormalities and Alters Neurogenesis

por Amiri, Anahita, Cho, Woosung, Zhou, Jing, Birnbaum, Shari G., Sinton, Christopher M., McKay, Renée M., Parada, Luis F.
Publicado no J Neurosci (2012)

A restricted cell population propagates glioblastoma growth following chemotherapy

por Chen, Jian, Li, Yanjiao, Yu, Tzong-Shiue, McKay, Renée M., Burns, Dennis K., Kernie, Steven G., Parada, Luis F.
Publicado em 2012

Ontological analyses reveal clinically-significant clear cell renal cell carcinoma subtypes with convergent evolutionary trajectories into an aggressive type

por Cai, Qi, Christie, Alana, Rajaram, Satwik, Zhou, Qinbo, Araj, Ellen, Chintalapati, Suneetha, Cadeddu, Jeffrey, Margulis, Vitaly, Pedrosa, Ivan, Rakheja, Dinesh, McKay, Renee M., Brugarolas, James, Kapur, Payal
Publicado no EBioMedicine (2019)

High-throughput simultaneous screen and counterscreen identifies homoharringtonine as synthetic lethal with von Hippel-Lindau loss in renal cell carcinoma

por Wolff, Nicholas C., Pavía-Jiménez, Andrea, Tcheuyap, Vanina T., Alexander, Shane, Vishwanath, Mridula, Christie, Alana, Xie, Xian-Jin, Williams, Noelle S., Kapur, Payal, Posner, Bruce, McKay, Renée M., Brugarolas, James
Publicado no Oncotarget (2015)

Corrigendum to ‘‘Ontological analyses reveal clinically-significant clear cell renal cell carcinoma subtypes with convergent evolutionary trajectories into an aggressive type’’ [EB...

por Cai, Qi, Christie, Alana, Rajaram, Satwik, Zhou, Qinbo, Araj, Ellen, Chintalapati, Suneetha, Singla, Nirmish, Cadeddu, Jeffrey, Margulis, Vitaly, Pedrosa, Ivan, Rakheja, Dinesh, McKay, Renee M., Brugarolas, James, Kapur, Payal
Publicado no EBioMedicine (2020)

Preclinical therapeutic efficacy of a novel pharmacological inducer of apoptosis in malignant peripheral nerve sheath tumors

por Chau, Vincent, Lim, S. Kyun, Mo, Wei, Liu, Chiachi, Patel, Amish J., McKay, Renée M., Wei, Shuguang, Posner, Bruce A., De Brabander, Jef K., Williams, Noelle S., Parada, Luis F., Le, Lu Q.
Publicado em 2013

PD-L1 detection using (89)Zr-atezolizumab immuno-PET in renal cell carcinoma tumorgrafts from a patient with favorable nivolumab response

por Vento, Joseph, Mulgaonkar, Aditi, Woolford, Layton, Nham, Kien, Christie, Alana, Bagrodia, Aditya, de Leon, Alberto Diaz, Hannan, Raquibul, Bowman, Isaac, McKay, Renee M., Kapur, Payal, Hao, Guiyang, Sun, Xiankai, Brugarolas, James
Publicado no J Immunother Cancer (2019)

Bap1 is essential for kidney function and cooperates with Vhl in renal tumorigenesis

por Wang, Shan-Shan, Gu, Yi-Feng, Wolff, Nicholas, Stefanius, Karoliina, Christie, Alana, Dey, Anwesha, Hammer, Robert E., Xie, Xian-Jin, Rakheja, Dinesh, Pedrosa, Ivan, Carroll, Thomas, McKay, Renée M., Kapur, Payal, Brugarolas, James
Publicado no Proc Natl Acad Sci U S A (2014)

Wnt signaling activation in adipose progenitors promotes insulin-independent muscle glucose uptake

por Zeve, Daniel, Seo, Jin, Suh, Jae Myoung, Stenesen, Drew, Tang, Wei, Berglund, Eric D., Wan, Yihong, Williams, Linda J., Lim, Ajin, Martinez, Myrna J., McKay, Renée M., Millay, Douglas P., Olson, Eric N., Graff, Jonathan M.
Publicado em 2012

CXCR4/CXCL12 mediate autocrine cell cycle progression in NF1-associated malignant peripheral nerve sheath tumors

por Mo, Wei, Chen, Jian, Patel, Amish, Zhang, Liang, Chau, Vincent, Li, Yanjiao, Cho, Woosung, Lim, Kyun, Xu, Jing, Lazar, Alexander J., Creighton, Chad J., Bolshakov, Svetlana, McKay, Renée M., Lev, Dina, Le, Lu Q., Parada, Luis F.
Publicado em 2013

Modeling Renal Cell Carcinoma in mice: Bap1 and Pbrm1 Inactivation Drive Tumor Grade

por Gu, Yi-Feng, Cohn, Shannon, Christie, Alana, McKenzie, Tiffani, Wolff, Nicholas, Do, Quyen N., Madhuranthakam, Ananth J., Pedrosa, Ivan, Wang, Tao, Dey, Anwesha, Busslinger, Meinrad, Xie, Xian-Jin, Hammer, Robert E., McKay, Renée M., Kapur, Payal, Brugarolas, James
Publicado no Cancer Discov (2017)

HIF-2 Complex Dissociation, Target Inhibition, and Acquired Resistance with PT2385, a First-in-Class HIF-2 Inhibitor in Clear Cell Renal Cell Carcinoma Patients

por Courtney, Kevin D., Ma, Yuanqing, de Leon, Alberto Diaz, Christie, Alana, Xie, Zhiqun, Woolford, Layton, Singla, Nirmish, Joyce, Allison, Hill, Haley, Madhuranthakam, Ananth J., Yuan, Qing, Xi, Yin, Zhang, Yue, Chang, Jenny, Fatunde, Oluwatomilade, Arriaga, Yull, Frankel, Arthur, Kalva, Sanjeeva, Zhang, Song, McKenzie, Tiffani, Torras, Oscar Reig, Figlin, Robert A., Rini, Brian I., McKay, Renée M., Kapur, Payal, Wang, Tao, Pedrosa, Ivan, Brugarolas, James
Publicado no Clin Cancer Res (2019)