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REDD1/DDIT4-independent mTORC1 Inhibition and Apoptosis by Glucocorticoids in Thymocytes
Glucocorticoids (GCs) induce apoptosis in lymphocytes and are commonly used to treat hematologic malignancies. However, they are also associated with significant adverse effects and their molecular mechanism of action is not fully understood. GC treatment induces expression of the mTORC1 inhibitor R...
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| Publicado no: | Mol Cancer Res |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4260655/ https://ncbi.nlm.nih.gov/pubmed/24615339 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-13-0625 |
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