Rapamycin inhibits mSin1 phosphorylation independently of mTORC1 and mTORC2

Current knowledge indicates that the mammalian target of rapamycin (mTOR) functions as two complexes, mTORC1 and mTORC2, regulating cell growth, proliferation, survival, differentiation, and motility. Recently mSin1 has been identified as a critical component of mTORC2, which is essential for phosph...

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Bibliographic Details
Published in:Oncotarget
Main Authors: Luo, Yan, Liu, Lei, Wu, Yang, Singh, Karnika, Su, Bing, Zhang, Nan, Liu, Xiaowei, Shen, Yangmei, Huang, Shile
Format: Artigo
Language:Inglês
Published: Impact Journals LLC 2015
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Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4414190/
https://ncbi.nlm.nih.gov/pubmed/25738366
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