Rapamycin inhibits mSin1 phosphorylation independently of mTORC1 and mTORC2

Current knowledge indicates that the mammalian target of rapamycin (mTOR) functions as two complexes, mTORC1 and mTORC2, regulating cell growth, proliferation, survival, differentiation, and motility. Recently mSin1 has been identified as a critical component of mTORC2, which is essential for phosph...

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Bibliografiske detaljer
Udgivet i:Oncotarget
Main Authors: Luo, Yan, Liu, Lei, Wu, Yang, Singh, Karnika, Su, Bing, Zhang, Nan, Liu, Xiaowei, Shen, Yangmei, Huang, Shile
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2015
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4414190/
https://ncbi.nlm.nih.gov/pubmed/25738366
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