Rapamycin inhibits mSin1 phosphorylation independently of mTORC1 and mTORC2

Current knowledge indicates that the mammalian target of rapamycin (mTOR) functions as two complexes, mTORC1 and mTORC2, regulating cell growth, proliferation, survival, differentiation, and motility. Recently mSin1 has been identified as a critical component of mTORC2, which is essential for phosph...

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發表在:Oncotarget
Main Authors: Luo, Yan, Liu, Lei, Wu, Yang, Singh, Karnika, Su, Bing, Zhang, Nan, Liu, Xiaowei, Shen, Yangmei, Huang, Shile
格式: Artigo
語言:Inglês
出版: Impact Journals LLC 2015
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Research Paper
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4414190/
https://ncbi.nlm.nih.gov/pubmed/25738366
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