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Direct physical interaction of active Ras with mSIN1 regulates mTORC2 signaling
BACKGROUND: The mechanistic (or mammalian) target of rapamycin (mTOR), a Ser/Thr kinase, associates with different subunits forming two functionally distinct complexes, mTORC1 and mTORC2, regulating a diverse set of cellular functions in response to growth factors, cellular energy levels, and nutrie...
Gorde:
| Argitaratua izan da: | BMC Cancer |
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| Egile Nagusiak: | , , , , , , , , , , , , , , , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
BioMed Central
2019
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6921532/ https://ncbi.nlm.nih.gov/pubmed/31856761 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-019-6422-6 |
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