Wnt signaling activation in adipose progenitors promotes insulin-independent muscle glucose uptake

Adipose tissues provide circulating nutrients and hormones. We present in vivo mouse studies highlighting roles for Wnt signals in both aspects of metabolism. β-catenin activation in PPARγ–expressing fat progenitors (PBCA) decreased fat mass and induced fibrotic replacement of subcutaneous fat speci...

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Hoofdauteurs: Zeve, Daniel, Seo, Jin, Suh, Jae Myoung, Stenesen, Drew, Tang, Wei, Berglund, Eric D., Wan, Yihong, Williams, Linda J., Lim, Ajin, Martinez, Myrna J., McKay, Renée M., Millay, Douglas P., Olson, Eric N., Graff, Jonathan M.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2012
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3325026/
https://ncbi.nlm.nih.gov/pubmed/22482731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2012.03.010
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