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Oestrogen signalling in white adipose progenitor cells inhibits differentiation into brown adipose and smooth muscle cells

Oestrogen, often via oestrogen receptor alpha (ERα) signalling, regulates metabolic physiology, highlighted by post-menopausal temperature dysregulation (hot flashes), glucose intolerance, increased appetite and reduced metabolic rate. Here we show that ERα signalling has a role in adipose lineage s...

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Bibliografiske detaljer
Udgivet i:Nat Commun
Main Authors: Lapid, Kfir, Lim, Ajin, Clegg, Deborah J., Zeve, Daniel, Graff, Jonathan M.
Format: Artigo
Sprog:Inglês
Udgivet: 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4770882/
https://ncbi.nlm.nih.gov/pubmed/25330806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms6196
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