Bap1 is essential for kidney function and cooperates with Vhl in renal tumorigenesis

Why different species are predisposed to different tumor spectra is not well understood. In particular, whether the physical location of tumor suppressor genes relative to one another influences tumor predisposition is unknown. Renal cancer presents a unique opportunity to explore this question. Ren...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Wang, Shan-Shan, Gu, Yi-Feng, Wolff, Nicholas, Stefanius, Karoliina, Christie, Alana, Dey, Anwesha, Hammer, Robert E., Xie, Xian-Jin, Rakheja, Dinesh, Pedrosa, Ivan, Carroll, Thomas, McKay, Renée M., Kapur, Payal, Brugarolas, James
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2014
Schlagworte:
Biological Sciences
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4246264/
https://ncbi.nlm.nih.gov/pubmed/25359211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1414789111
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