Loss of PBRM1 and BAP1 Expression Is Less Common in Non–Clear Cell Renal Cell Carcinoma Than in Clear Cell Renal Cell Carcinoma

BACKGROUND: Recurrent mutations in polybromo-1 (PBRM1, ~40%) and BRCA1-associated protein-1 (BAP1, ~10%) occur in clear cell renal cell carcinoma (ccRCC), but their prevalence in non clear cell renal cell carcinoma (non-ccRCC) or renal oncocytoma (RO) is unknown. We evaluated loss of PBRM1 and BAP1...

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Vydáno v:Urol Oncol
Hlavní autoři: Ho, Thai H., Kapur, Payal, Joseph, Richard W., Serie, Daniel J., Eckel-Passow, Jeanette E., Parasramka, Mansi, Cheville, John C., Wu, Kevin J., Frenkel, Eugene, Rakheja, Dinesh, Stefanius, Karoliina, Brugarolas, James, Parker, Alexander S.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4274200/
https://ncbi.nlm.nih.gov/pubmed/25465300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.urolonc.2014.10.014
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