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Loss of BAP1 Protein Expression Is an Independent Marker of Poor Prognosis in patients with Low Risk Clear Cell Renal Cell Carcinoma
PURPOSE: The majority of patients diagnosed with clear cell renal cell carcinoma (ccRCC) have low-risk disease with a <10% chance of ccRCC-specific death. DNA sequencing revealed that mutations in BAP1 occur in 5–15% of ccRCC and are associated with poor outcomes. The vast majority of BAP1 mutati...
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| Autori principali: | , , , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2013
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4075029/ https://ncbi.nlm.nih.gov/pubmed/24382589 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cncr.28521 |
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