Higher Expression of Topoisomerase II Alpha Is an Independent Marker of Increased Risk of Cancer-specific Death in Patients with Clear Cell Renal Cell Carcinoma

BACKGROUND: Tumor-based biomarkers of outcome for patients with clear cell renal cell carcinoma (ccRCC) remain limited, especially for those with low-risk disease. Type IIa topoisomerase (TOPOIIa) is a well-known biomarker of DNA replication and a target for antineoplastic agents, but it has not bee...

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Main Authors: Parker, Alexander S., Eckel-Passow, Jeanette E., Serie, Daniel, Hilton, Tracy, Parasramka, Mansi, Joseph, Richard, Wu, Kevin, Cheville, John C., Leibovich, Bradley C.
Format: Artigo
Jezik:Inglês
Izdano: 2013
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4071134/
https://ncbi.nlm.nih.gov/pubmed/24388441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.eururo.2013.12.017
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