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C. elegans: A Model for Exploring the Genetics of Fat Storage

To gain insights into the genetic cascades that regulate fat biology, we evaluated C. elegans as an appropriate model organism. We generated worms that lack two transcription factors, SREBP and C/EBP, crucial for formation of mammalian fat. Worms deficient in either of these genes displayed a lipid-...

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書目詳細資料
發表在:Dev Cell
Main Authors: McKay, Renée M., McKay, James P., Avery, Leon, Graff, Jonathan M.
格式: Artigo
語言:Inglês
出版: 2003
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4445237/
https://ncbi.nlm.nih.gov/pubmed/12530969
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