PERK in beta cell biology and insulin biogenesis

Por Cavener, Douglas R., Gupta, Sounak, McGrath, Barbara C.
Publicado em 2010

GCN2 in the Brain Programs PPARγ2 and Triglyceride Storage in the Liver during Perinatal Development in Response to Maternal Dietary Fat

Por Xu, Xu, Hu, Jingjie, McGrath, Barbara C., Cavener, Douglas R.
Publicado em 2013

GCN2 regulates the CCAAT enhancer binding protein beta and hepatic gluconeogenesis

Por Xu, Xu, Hu, Jingjie, McGrath, Barbara C., Cavener, Douglas R.
Publicado em 2013

PERK Regulates Working Memory and Protein Synthesis-Dependent Memory Flexibility

Por Zhu, Siying, Henninger, Keely, McGrath, Barbara C., Cavener, Douglas R.
Publicado no PLoS One (2016)

PERK eIF2 alpha kinase is required to regulate the viability of the exocrine pancreas in mice

Por Iida Kaori, Li Yulin, McGrath Barbara C, Frank Ami, Cavener Douglas R
Publicado em 2007-08-01

PERK eIF2 alpha kinase is required to regulate the viability of the exocrine pancreas in mice

Por Iida, Kaori, Li, Yulin, McGrath, Barbara C, Frank, Ami, Cavener, Douglas R
Publicado em 2007

Acute ablation of PERK results in ER dysfunctions followed by reduced insulin secretion and cell proliferation

Por Feng, Daorong, Wei, Jianwen, Gupta, Sounak, McGrath, Barbara C, Cavener, Douglas R
Publicado em 2009

Hyperthermia Induces the ER Stress Pathway

Por Xu, Xu, Gupta, Sounak, Hu, Wenli, McGrath, Barbara C., Cavener, Douglas R.
Publicado em 2011

PERK regulates G(q) protein-coupled intracellular Ca(2+) dynamics in primary cortical neurons

Por Zhu, Siying, McGrath, Barbara C., Bai, Yuting, Tang, Xin, Cavener, Douglas R.
Publicado no Mol Brain (2016)

Perk Gene Dosage Regulates Glucose Homeostasis by Modulating Pancreatic β-Cell Functions

Por Wang, Rong, Munoz, Elyse E., Zhu, Siying, McGrath, Barbara C., Cavener, Douglas R.
Publicado em 2014

Insulin Secretion and Ca(2+) Dynamics in β-Cells Are Regulated by PERK (EIF2AK3) in Concert with Calcineurin

Por Wang, Rong, McGrath, Barbara C., Kopp, Richard F., Roe, Michael W., Tang, Xin, Chen, Gong, Cavener, Douglas R.
Publicado em 2013

Phosphorylation of the α Subunit of Eukaryotic Initiation Factor 2 Is Required for Activation of NF-κB in Response to Diverse Cellular Stresses

Por Jiang, Hao-Yuan, Wek, Sheree A., McGrath, Barbara C., Scheuner, Donalyn, Kaufman, Randal J., Cavener, Douglas R., Wek, Ronald C.
Publicado em 2003

Activating Transcription Factor 3 Is Integral to the Eukaryotic Initiation Factor 2 Kinase Stress Response

Por Jiang, Hao-Yuan, Wek, Sheree A., McGrath, Barbara C., Lu, Dan, Hai, Tsonwin, Harding, Heather P., Wang, Xiaozhong, Ron, David, Cavener, Douglas R., Wek, Ronald C.
Publicado em 2004

The protein kinase PERK/EIF2AK3 regulates proinsulin processing not via protein synthesis but by controlling endoplasmic reticulum chaperones

Por Sowers, Carrie R., Wang, Rong, Bourne, Rebecca A., McGrath, Barbara C., Hu, Jingjie, Bevilacqua, Sarah C., Paton, James C., Paton, Adrienne W., Collardeau-Frachon, Sophie, Nicolino, Marc, Cavener, Douglas R.
Publicado no J Biol Chem (2018)

The GCN2 eIF2α Kinase Is Required for Adaptation to Amino Acid Deprivation in Mice

Por Zhang, Peichuan, McGrath, Barbara C., Reinert, Jamie, Olsen, DeAnne S., Lei, Li, Gill, Sangeeta, Wek, Sheree A., Vattem, Krishna M., Wek, Ronald C., Kimball, Scot R., Jefferson, Leonard S., Cavener, Douglas R.
Publicado em 2002

Giraffe genome sequence reveals clues to its unique morphology and physiology

Por Agaba, Morris, Ishengoma, Edson, Miller, Webb C., McGrath, Barbara C., Hudson, Chelsea N., Bedoya Reina, Oscar C., Ratan, Aakrosh, Burhans, Rico, Chikhi, Rayan, Medvedev, Paul, Praul, Craig A., Wu-Cavener, Lan, Wood, Brendan, Robertson, Heather, Penfold, Linda, Cavener, Douglas R.
Publicado no Nat Commun (2016)