A carregar...

Insulin Secretion and Ca(2+) Dynamics in β-Cells Are Regulated by PERK (EIF2AK3) in Concert with Calcineurin

Protein kinase R (PKR)-like endoplasmic reticulum kinase (PERK) (EIF2AK3) is essential for normal development and function of the insulin-secreting β-cell. Although genetic ablation of PERK in β-cells results in permanent neonatal diabetes in humans and mice, the underlying mechanisms remain unclear...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Wang, Rong, McGrath, Barbara C., Kopp, Richard F., Roe, Michael W., Tang, Xin, Chen, Gong, Cavener, Douglas R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3837125/
https://ncbi.nlm.nih.gov/pubmed/24114838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.503664
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!