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PERK Regulates Working Memory and Protein Synthesis-Dependent Memory Flexibility
PERK (EIF2AK3) is an ER-resident eIF2α kinase required for memory flexibility and metabotropic glutamate receptor-dependent long-term depression, processes known to be dependent on new protein synthesis. Here we investigated PERK’s role in working memory, a cognitive ability that is independent of n...
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Publicado no: | PLoS One |
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Main Authors: | , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Public Library of Science
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5023101/ https://ncbi.nlm.nih.gov/pubmed/27627766 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0162766 |
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