PERK regulates G(q) protein-coupled intracellular Ca(2+) dynamics in primary cortical neurons

PERK (EIF2AK3) is an ER-resident eIF2α kinase required for behavioral flexibility and metabotropic glutamate receptor-dependent long-term depression via its translational control. Motivated by the recent discoveries that PERK regulates Ca(2+) dynamics in insulin-secreting β-cells underlying glucose-...

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Publicat a:Mol Brain
Autors principals: Zhu, Siying, McGrath, Barbara C., Bai, Yuting, Tang, Xin, Cavener, Douglas R.
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2016
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5045583/
https://ncbi.nlm.nih.gov/pubmed/27716400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13041-016-0268-5
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