Hyperthermia Induces the ER Stress Pathway

BACKGROUND: The ER chaperone GRP78/BiP is a homolog of the Hsp70 family of heat shock proteins, yet GRP78/BiP is not induced by heat shock but instead by ER stress. However, previous studies had not considered more physiologically relevant temperature elevation associated with febrile hyperthermia....

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Bibliografiske detaljer
Main Authors: Xu, Xu, Gupta, Sounak, Hu, Wenli, McGrath, Barbara C., Cavener, Douglas R.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2011
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3158104/
https://ncbi.nlm.nih.gov/pubmed/21876766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0023740
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