Integrating p38α-MAPK immune signals in non-immune cells

Por Gaffen, Sarah L., McGeachy, Mandy
Publicado no Sci Signal (2015)

CD73 is expressed by inflammatory Th17 cells in experimental autoimmune encephalomyelitis but does not limit differentiation or pathogenesis

Por Hernandez-Mir, Gerard, McGeachy, Mandy J.
Publicado no PLoS One (2017)

Microbial-induced Th17: Superhero or Supervillain?

Por McGeachy, Mandy J., McSorley, Stephen J.
Publicado em 2012

Neuroinflammation in the Evolution of Secondary Injury, Repair, and Chronic Neurodegeneration after Traumatic Brain Injury

Por Simon, Dennis W., McGeachy, Mandy, Bayır, Hülya, Clark, Robert S.B., Loane, David J., Kochanek, Patrick M.
Publicado no Nat Rev Neurol (2017)

Interleukin-23 Drives Intestinal Inflammation through Direct Activity on T Cells

Por Ahern, Philip P., Schiering, Chris, Buonocore, Sofia, McGeachy, Mandy J., Cua, Dan J., Maloy, Kevin J., Powrie, Fiona
Publicado em 2010

Interleukin-23 Drives Intestinal Inflammation through Direct Activity on T Cells

Por Ahern, Philip P., Schiering, Chris, Buonocore, Sofia, McGeachy, Mandy J., Cua, Dan J., Maloy, Kevin J., Powrie, Fiona
Publicado em 2011

mTORC2 deficiency in myeloid DC enhances their allogeneic Th1 and Th17 stimulatory ability after TLR4 ligation in vitro and in vivo

Por Raïch-Regué, Dàlia, Rosborough, Brian R., Watson, Alicia R., McGeachy, Mandy J., Turnquist, Hēth R., Thomson, Angus W.
Publicado no J Immunol (2015)

Analysis of CXCR5(+)Th17 cells in relation to disease activity and TNF inhibitor therapy in Rheumatoid Arthritis

Por Singh, Deepika, Henkel, Matthew, Sendon, Bernadette, Feng, June, Fabio, Anthony, Metes, Diana, Moreland, Larry W., McGeachy, Mandy J.
Publicado no Sci Rep (2016)

Activation of MDL-1 (CLEC5A) on immature myeloid cells triggers lethal shock in mice

Por Cheung, Ricky, Shen, Fran, Phillips, Joseph H., McGeachy, Mandy J., Cua, Daniel J., Heyworth, Paul G., Pierce, Robert H.
Publicado em 2011

IL-23 and IL-1β Drive Human Th17 Cell Differentiation and Metabolic Reprogramming in Absence of CD28 Costimulation

Por Revu, Shankar, Wu, Jing, Henkel, Matthew, Rittenhouse, Natalie, Menk, Ashley, Delgoffe, Greg M., Poholek, Amanda C., McGeachy, Mandy J.
Publicado no Cell Rep (2018)

Disease associated anti-citrullinated protein memory B cells in rheumatoid arthritis persist in clinical remission

Por Pelzek, Adam J., Grönwall, Caroline, Rosenthal, Pamela, Greenberg, Jeffrey D., McGeachy, Mandy, Moreland, Larry, Rigby, William F.C., Silverman, Gregg J.
Publicado no Arthritis Rheumatol (2017)

Rheumatoid arthritis patients exhibit impaired Candida albicans-specific Th17 responses

Por Bishu, Shrinivas, Su, Ee Wern, Wilkerson, Erich R, Reckley, Kelly A, Jones, Donald M, McGeachy, Mandy J, Gaffen, Sarah L, Levesque, Marc C
Publicado em 2014

A Candida albicans Strain Expressing Mammalian Interleukin-17A Results in Early Control of Fungal Growth during Disseminated Infection

Por Huppler, Anna R., Whibley, Natasha, Woolford, Carol A., Childs, Erin E., He, Jie, Biswas, Partha S., McGeachy, Mandy J., Mitchell, Aaron P., Gaffen, Sarah L.
Publicado no Infect Immun (2015)

CCAAT/Enhancer-binding protein β promotes pathogenesis of EAE

Por Simpson-Abelson, Michelle R., Hernandez-Mir, Gerard, Childs, Erin E., Cruz, J. Agustin, Poholek, Amanda C., Chattopadhyay, Ansuman, Gaffen, Sarah L., McGeachy, Mandy J.
Publicado no Cytokine (2017)

Interleukin 23 receptor is essential for terminal differentiation of effector T helper type 17 cells in vivo

Por McGeachy, Mandy J, Chen, Yi, Tato, Cristina M, Laurence, Arian, Joyce-Shaikh, Barbara, Blumenschein, Wendy, McClanahan, Terrill, O’Shea, John J, Cua, Daniel J
Publicado em 2009

Inflammatory Th17 Cells Express Integrin α(v)β(3) for Pathogenic Function

Por Du, Fang, Garg, Abhishek V., Kosar, Karis, Majumder, Saikat, Kugler, David G., Mir, Gerard Hernandez, Maggio, Maria, Henkel, Matthew, Lacy-Hulbert, Adam, McGeachy, Mandy J.
Publicado no Cell Rep (2016)

Prostaglandin E2 regulates Th17 cell differentiation and function through cyclic AMP and EP2/EP4 receptor signaling

Por Boniface, Katia, Bak-Jensen, Kristian S., Li, Ying, Blumenschein, Wendy M., McGeachy, Mandy J., McClanahan, Terrill K., McKenzie, Brent S., Kastelein, Robert A., Cua, Daniel J., de Waal Malefyt, René
Publicado em 2009

Delinking CARD9 and IL-17: CARD9 Protects against Candida tropicalis Infection through a TNF-α–Dependent, IL-17–Independent Mechanism

Por Whibley, Natasha, Jaycox, Jillian R., Reid, Delyth, Garg, Abhishek V., Taylor, Julie A., Clancy, Cornelius J., Nguyen, M. Hong, Biswas, Partha S., McGeachy, Mandy J., Brown, Gordon D., Gaffen, Sarah L.
Publicado no J Immunol (2015)

MCPIP1 endoribonuclease activity negatively regulates interleukin-17-mediated signaling and inflammation

Por Garg, Abhishek V., Amatya, Nilesh, Chen, Kong, Cruz, J. Agustin, Grover, Prerna, Whibley, Natasha, Conti, Heather R., Mir, Gerard Hernandez, Sirakova, Tatiana, Childs, Erin C., Smithgall, Thomas E., Biswas, Partha S., Kolls, Jay K., McGeachy, Mandy J., Kolattukudy, Pappachan E., Gaffen, Sarah L.
Publicado no Immunity (2015)

Oral epithelial cells orchestrate innate Type 17 responses to Candida albicans through the virulence factor Candidalysin

Por Verma, Akash H., Richardson, Jonathan P., Zhou, Chunsheng, Coleman, Bianca M., Moyes, David L., Ho, Jemima, Huppler, Anna R., Ramani, Kritika, McGeachy, Mandy J., Mufazalov, Ilgiz A., Waisman, Ari, Kane, Lawrence P., Biswas, Partha S., Hube, Bernhard, Naglik, Julian R., Gaffen, Sarah L.
Publicado no Sci Immunol (2017)