Oral epithelial cells orchestrate innate Type 17 responses to Candida albicans through the virulence factor Candidalysin

Candida albicans is a dimorphic commensal fungus that causes severe oral infections in immunodeficient patients. Invasion of C. albicans hyphae into oral epithelium is an essential virulence trait. IL-17 signaling is required for both innate and adaptive immunity to C. albicans. During the innate re...

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Publicado no:Sci Immunol
Main Authors: Verma, Akash H., Richardson, Jonathan P., Zhou, Chunsheng, Coleman, Bianca M., Moyes, David L., Ho, Jemima, Huppler, Anna R., Ramani, Kritika, McGeachy, Mandy J., Mufazalov, Ilgiz A., Waisman, Ari, Kane, Lawrence P., Biswas, Partha S., Hube, Bernhard, Naglik, Julian R., Gaffen, Sarah L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5881387/
https://ncbi.nlm.nih.gov/pubmed/29101209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciimmunol.aam8834
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