Candidalysin Is Required for Neutrophil Recruitment and Virulence During Systemic Candida albicans Infection

BACKGROUND: Candidalysin is a cytolytic peptide toxin secreted by Candida albicans hyphae and has significantly advanced our understanding of fungal pathogenesis. Candidalysin is critical for mucosal C albicans infections and is known to activate epithelial cells to induce downstream innate immune r...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:J Infect Dis
Autori principali: Swidergall, Marc, Khalaji, Mina, Solis, Norma V, Moyes, David L, Drummond, Rebecca A, Hube, Bernhard, Lionakis, Michail S, Murdoch, Craig, Filler, Scott G, Naglik, Julian R
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2019
Soggetti:
Major Articles and Brief Reports
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6761979/
https://ncbi.nlm.nih.gov/pubmed/31401652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiz322
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