Delinking CARD9 and IL-17: CARD9 Protects against Candida tropicalis Infection through a TNF-α–Dependent, IL-17–Independent Mechanism

Candida is the third most common cause of bloodstream infections in hospitalized patients. Immunity to C. albicans, the most frequent species to be isolated in candidiasis, involves a well-characterized Dectin-1/caspase-associated recruitment domain adaptor 9 (CARD9)/IL-17 signaling axis. Infections...

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Enregistré dans:
Détails bibliographiques
Publié dans:J Immunol
Auteurs principaux: Whibley, Natasha, Jaycox, Jillian R., Reid, Delyth, Garg, Abhishek V., Taylor, Julie A., Clancy, Cornelius J., Nguyen, M. Hong, Biswas, Partha S., McGeachy, Mandy J., Brown, Gordon D., Gaffen, Sarah L.
Format: Artigo
Langue:Inglês
Publié: AAI 2015
Sujets:
Infectious Disease and Host Response
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4592105/
https://ncbi.nlm.nih.gov/pubmed/26336150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1500870
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