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Disease associated anti-citrullinated protein memory B cells in rheumatoid arthritis persist in clinical remission
OBJECTIVE: In RA, autoreactive B cells are pathogenic drivers and sources of anti-citrullinated protein antibodies (ACPA) that serve as a diagnostic biomarker and predictor of worse long-term prognosis. Yet the immunobiologic significance of persistent ACPA production at a cellular level is poorly u...
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Publicado no: | Arthritis Rheumatol |
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Main Authors: | , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2017
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5569882/ https://ncbi.nlm.nih.gov/pubmed/28118534 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.40053 |
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