Rheumatoid arthritis patients exhibit impaired Candida albicans-specific Th17 responses

INTRODUCTION: Accumulating data implicate the CD4+ T cell subset (Th17 cells) in rheumatoid arthritis (RA). IL-17 is an inflammatory cytokine that induces tumor necrosis factor (TNF)α, IL-1β and IL-6, all of which are targets of biologic therapies used to treat RA. RA patients are well documented to...

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Detalhes bibliográficos
Main Authors: Bishu, Shrinivas, Su, Ee Wern, Wilkerson, Erich R, Reckley, Kelly A, Jones, Donald M, McGeachy, Mandy J, Gaffen, Sarah L, Levesque, Marc C
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3978747/
https://ncbi.nlm.nih.gov/pubmed/24513269
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar4480
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