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mTORC2 deficiency in myeloid DC enhances their allogeneic Th1 and Th17 stimulatory ability after TLR4 ligation in vitro and in vivo
The mammalian/mechanistic target of rapamycin (mTOR) is a key integrative kinase that functions in two independent complexes, mTOR complex (mTORC) 1 and mTORC2. In contrast to the well-defined role of mTORC1 in dendritic cells (DC), little is known about the function of mTORC2. Here, we demonstrate...
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| Publicado no: | J Immunol |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4417394/ https://ncbi.nlm.nih.gov/pubmed/25840913 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1402551 |
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